Animal Models Content

Portfolio Introduction

Vivipro Biolabs maintains actively breeding colonies of diverse, high-quality rodent and lagomorph models, carefully selected to support a broad spectrum of biomedical research applications. The availability of both commonly used and specialized strains allows the organization to cater to routine testing requirements as well as cutting-edge research in areas like oncology and immunology. All animals are bred and housed within Vivipro Biolabs’ state-of-the-art, environmentally controlled vivarium, ensuring optimal living conditions. Furthermore, they are maintained under strict health monitoring protocols, providing researchers with confidence in the health status and reliability of the models supplied for their critical studies.

Detailed Model Listings

Vivipro Biolabs provides the following research models, organized by species:

Rats:

Wistar (Wistar IGS Rats): A widely used outbred stock for general toxicology, pharmacology, and physiology studies.
Sprague Dawley (CD (SD)® IGS Rat): Another popular outbred stock known for its calm temperament and utility in toxicology, reproduction, and behavioral research.

Mice:

Swiss Albino (RjOrl:SWISS): An outbred strain valued for its vigor and productivity, commonly used in safety testing and general research applications. Origin Note: This strain originates from albino mice imported to the Rockefeller Institute by Lynch in 1926, with subsequent selection by Carworth Farm.
BALB/c (BALB/c Mice): An inbred strain widely used in immunology (especially for monoclonal antibody production) and infectious disease research.
C57BL/6N (C57BL/6N Mice): A commonly used inbred strain, serving as the background for many transgenic models; utilized extensively in immunology, genetics, and neurobiology.
CD-1® ICR Mice: An outbred mouse stock frequently used in safety and efficacy testing, toxicology, and as recipients for embryo transfer.
Athymic Nude (Foxn1nu) Mice: Immunodeficient mice lacking a thymus, essential for tumor xenograft studies in oncology research.
Fox Chase SCID® Beige Mice: Severely immunodeficient mice lacking functional T and B cells, with impaired NK cell function; suitable for engraftment of human hematopoietic cells and tumors.
NOD SCID Mice: Non-obese diabetic mice with the SCID mutation, providing a model of severe combined immunodeficiency often used for human cell engraftment and studies of diabetes and autoimmunity.
DBA/2 Mice: An inbred strain used in immunology, neurobiology, and audiology research; known for susceptibility to certain autoimmune conditions.
C3H Mice: An inbred strain often used in oncology (mammary tumor research), immunology, and inflammation studies.

Rabbits:

New Zealand White: A large rabbit breed commonly used for antibody production, toxicology (e.g., Draize test), and cardiovascular research.

Guinea Pigs:

Dunkin Hartley: An outbred albino strain frequently used in immunology (particularly hypersensitivity studies like GPMT), infectious disease research, and nutritional studies.

Table 2: Available Research Animal Models at Vivipro Biolabs

Species	Strain Name	Key Characteristics / Common Use Area
Rats	Wistar (IGS)	Outbred; General toxicology, pharmacology, physiology
	Sprague Dawley (CD® SD® IGS)	Outbred; Toxicology, reproduction, behavior
Mice	Swiss Albino (RjOrl:SWISS)	Outbred; General purpose, safety testing
	BALB/c	Inbred; Immunology, antibody production, infectious disease
	C57BL/6N	Inbred; Immunology, genetics, neurobiology, transgenic bg
	CD-1® ICR	Outbred; Safety/efficacy testing, toxicology
	Athymic Nude (Foxn1nu)	Immunodeficient (T-cell); Oncology (xenografts)
	Fox Chase SCID® Beige	Immunodeficient (T-, B-, NK cell defects); Engraftment
	NOD SCID	Immunodeficient (T-, B-cell); Diabetes, engraftment
	DBA/2	Inbred; Immunology, neurobiology, audiology
	C3H	Inbred; Oncology, immunology, inflammation
Rabbits	New Zealand White	Outbred; Antibody production, toxicology, cardiovascular
Guinea Pigs	Dunkin Hartley	Outbred; Immunology (hypersensitivity), infectious disease

This diverse portfolio demonstrates Vivipro Biolabs’ capacity to support a wide array of preclinical research endeavors, from routine screening to specialized disease modeling.